Traditional organoid cultures suffer from overlapping growth, heterogeneity, and retrieval challenges. The CellRaft AIR® System solves these issues with automated imaging and isolation for high-quality 3D organoid culture.

• Grow & track hundreds of organoids over time
• Perform on-array phenotypic assessment
• Fully automate isolation of viable, intact organoids
• Generate customized 96-well plates for organoid-based assays (clonal propagation, drug screening, target discovery)

• Z-stack imaging captures organoid structure in brightfield & fluorescence
• CellRaft Cytometry™ enables track-and-trace clonality verification
• AI-driven selection based on morphology, size, and fluorescence intensity

Detailed phenotypic images are cataloged and easily exported for analysis. Our intuitive software enables one-touch, full-array image scanning for seamless data capture.

Brightfield Imaging of Mouse Hepatic Organoids / EpCAM & Hoechst Imaging of Mouse Hepatic Organoids

Use CellRaft Cytometry™ to identify CellRafts with 3D structures of interest, detecting organoids and verifying single-cell clonality, morphology, and growth rate. These critical data points ensure track-and-traceability for clonality confirmation. Selected organoids can be further evaluated based on diameter, circularity, and fluorescence intensity.

Perform phenotypic characterization with Raft Cytometry. /  Identify and verify CellRafts containing 3D structures of interest and create sets of sub-populations for isolation

The AIR System’s 3D capabilities allow for damage-free organoid retrieval, preserving viability for further growth and research.