Challenges using Traditional Organoid Cultures
Overlapping structures, requiring expensive multifocal imaging.
Heterogeneity in viability and phenotype.
Retrieval challenges due to viscous extracellular matrix.
Key Advantages CellRaft AIR® System
The CellRaft
AIR® System solves these issues with automated imaging and isolation for
high-quality 3D organoid culture.
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Grow & track hundreds of
organoids over time
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Perform on-array phenotypic
assessment
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Fully automate isolation of viable,
intact organoids
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Generate customized 96-well plates
for organoid-based assays (clonal propagation, drug screening, target
discovery)
Advanced Imaging & Analysis
- Z-stack imaging captures organoid structure in brightfield & fluorescence
- CellRaft Cytometry™ enables track-and-trace clonality verification
- AI-driven selection based on morphology, size, and fluorescence intensity
- Detailed phenotypic images are cataloged and easily exported for analysis
Our intuitive software enables one-touch, full-array image scanning for seamless data capture.
Brightfield Imaging of Mouse Hepatic Organoids / EpCAM & Hoechst Imaging of Mouse Hepatic Organoids
CellRaft Cytometry™ identifies CellRafts containing 3D structures of interest, detecting organoids and verifying single-cell clonality, morphology, and growth rate. These critical data points ensure track-and-traceability for clonality confirmation. Selected organoids can be further evaluated based on diameter, circularity, and fluorescence intensity.
Perform phenotypic characterization with Raft Cytometry. / Identify and verify CellRafts containing 3D structures of interest and create sets of sub-populations for isolation
Gentle, Automated Isolation
The CellRaft
AIR® System’s 3D capabilities allow for
damage-free organoid retrieval, preserving viability for further growth and
research.
