Cell Therapy Potency Assays and Release Testing
Instruments, cell culture consumables and services for every stage of cell therapy development — from stem and immune cell therapies through to potency assays and release testing.
Cell Therapy – Accelerate Discovery to Preclinical Success
Cell therapy is a medical approach using living cells to repair, replace, or restore damaged tissues or to fight diseases such as cancer. The cells can come from the patient (autologous), from a donor (allogeneic) or can be engineered cells from standardized and scalable cell lines.
OLS – Your Partner in Cell Research – provides high-quality instruments, cell culture consumables, and tailored services to enhance efficiency, reproducibility, and data reliability across all stages of cell therapy development.
Key Areas of Cell Therapy
Cell therapy encompasses several therapeutic strategies designed to restore tissue function or eliminate diseased cells:
1. Stem Cell Therapies
- iPSCs for future regenerative applications
- Mesenchymal stem cells (inflammation, joint repair)
- Hematopoietic stem cells (blood cancers)
2. Immune Cell Therapies
- CAR-T cell therapies
- TCR-T therapies
- NK cell therapies
- Dendritic cell vaccines
3. Tissue-Specific Cell Replacement
- Islet cells for diabetes
- Chondrocytes for cartilage
- Ongoing research for heart, liver, retina, and neural repair
OLS Technologies Supporting Cell Therapy Research
OLS provides a full technology platform for developing, engineering, analyzing, expanding, and banking therapeutic cells.
1. Stem Cell Therapy Solutions
Induced pluripotent stem cells (iPSC) can be differentiated into nearly any cell type. Once differentiated, these cells can be administered autologously or allogeneically to restore or replace damaged tissues.
Mesenchymal stem/stromal cells (MSC) can be directed to form chondrocytes, adipocytes, and osteoblasts, supporting the regeneration of cartilage, adipose tissue, and bone.
Together, iPSC and MSC technologies provide powerful tools for tissue repair, regenerative medicine, and advanced cell therapy development.
OLS´s stem cell workflow supports every step: From expansion and differentiation to reliable cryopreservation - ensuring high-quality, reproducible results for cutting-edge research.
Key Technologies for iPSC & MSC Research
Tissue dissociation
Cell counting
Stem cell culture
Expansion & 3D culture
Sorting single cells and organoids
High content imaging
Grow key hematopoietic cell populations with:
- HiMarrowXL™- high-quality karyotyping medium, suitable for in vitro cultures of bone marrow cells assuring a high mitotic index, ideal chromosome resolution
- HiSep™ Lymphocyte Separation Media (LSM) - enables simple isolation of mononuclear cells from blood
- IMDM – nutrient-rich medium for optimal HSC culture
2. Solutions for Immune Cell Therapies
1. Real-Time Potency & Cytotoxicity Testing
Quantify T-cell cytotoxicity and evaluate the potency of CAR-T constructs quickly and accurately using xCELLigence Real Time Cell Analysis (RTCA) System.
Label-free real-time monitoring of:
- Target-cell adhesion and proliferation
- Potency of CAR-T constructs
- Cytolytic activity
- Specificity and efficiency of engineered T cells
Across multiple constructs, the xCELLigence RTCA clearly identifies the most effective CAR-T design. Ideal for applications including cytotoxicity, proliferation, invasion/migration, virology, cardio-toxicity, and barrier function studies.
Enhance experimental reproducibility with:
- smarT™ – complete serum-free, xeno-free medium optimized for T-cell expansion and activation.
2. Flow Cytometry for Immunophenotyping
NovoCyte Flow Cytometers combined with Proteintech antibodies (CD markers) provide precise characterization of:
- T-cell subsets (e.g., for CAR-T development)
- PBMC subpopulations
- Newly developed cell lines
- Hematopoietic stem cells (HSCs)
Together, these tools enable high-quality immunophenotyping.
3. Reliable Cell Quality Control
Quality control is essential for any cells intended for patient use. OLS provides trusted QC tools:
- Cell Counting: CASY Cell Counter & Analyzer
- Real-Time Cell Analysis: xCELLigence RTCA systems
- Live Cell Imaging: zenCELL owl incubator microscope and xCELLigence eSight
- Mycoplasma detection (EZdetect) & elimination kits (EZkill)
Routine QC helps support Corrective and Preventive Action (CAPA) processes, reduces experimental failure, and improves long-term reproducibility.
Invite our experts and lift your research to the next stage with a demo CERO 3D Incubator and Bioreactor from OLS
Join OLS and make your research reliable with our CERO 3D Incubator and Bioreactor with your lab-services as results.