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xCELLigence Real-Time Cell Analysis systems

Highly sensitive, non-invasive, easy to operate - crafted for visionary researchers, emphasizing precision and innovation.


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Using the xCELLigence Real-Time Cell Analyzer, you can monitor your cell numbers, cell-cell contacts, cell morphology over time as well as their migratory and invasive properties.



For virology research, virus-infected cells often display the cytopathic effect (CPE), reflecting morphological changes, cell fusion, lysis or the formation of inclusion bodies. Our Live Cell Analysis System xCELLigence allows detection of subtle changes occurring during CPE, like changes in cell-surface adhesion that can easily be missed by microscopy.

Indeed, the xCELLigence Real-Time Cell Analyzer allows you to study cells in co-culture as well. Secretory proteins such as cytokines and chemokines, can lead to induction or reduction of cell proliferation, altering in normal cell development and tumorigenesis. 

Highly Sensitive: The impedance-based technology is highly sensitive, allowing very low effector to target ratios. Continuous cell monitoring in real time enables investigation of short- and long-term effects. As a result, a full kinetic read out of the cellular behaviour is obtained- objective and quantitative.

Non-Invasive: xCELLigence® requires no cell labeling, which increases the physiological relevance and reduces the workload.

Easy to operate: Now run your cell-based assays with xCELLigence® RTCA easily. Literally! Click on RUN button and RELAX



xCELLigence - Products Overview


RTCA S16


  • 1 x 16 well format
  • Maximum throughput: 16 wells
  • Assays
  • QC, proliferation, cytotoxicity, adhesion, receptor signaling
  • Specialty:
  •  Uncomplicated assay development & optimization  

RTCA DP


  • 3 x 16 well format
  • Maximum throughput: 48 wells
  • Assays
  • QC, proliferation, cytotoxicity, adhesion, receptor signaling
  • Specialty
  • Cell invasion & migration assays with dedicated CIM plates

RTCA SP


  • 1 x 96 well format
  • Maximum throughput: 96 wells
  • Assays
  • QC, proliferation, cytotoxicity, adhesion, receptor signaling
  • Specialty
  • Measures the 96 well plate within only approx. 7 seconds

RTCA MP


  • 6 x 96 well format
  • Maximum throughput: 576 wells
  • Assays
  • QC, proliferation, cytotoxicity, adhesion, receptor signaling
  • Specialty
  • 6 parallel & independent analyses to maximize productivity

RTCA eSight


  • 5 x 96 well format
  • 5 cradles with live-cell fluorescence imaging
  • Assays
  • proliferation, cytotox, apoptosis, co-culture, fast kinetics and more
  • Specialty
  • 3 cradles combining imaging & impedance analysis

Highlights - Live Cell Analysis System xCELLigence 


  • Continuously monitor live cell proliferation, morphology and viability
  • No cell labeling required
  • Impedance-based real-time analysis
  • Different throughputs from 16 to 4×384 well formats
  • Kinetic read-out – capture both short (sec) and long-term effects (days)
  • Easy – Walk-away operation
  • Exceeds limitations from endpoint-assays
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