Spheroid Plates for Reliable 3D Cell Culture

CEROplate Ultra-Low-Attachment: Unmatched performance and reliability for spheroid culture

CEROplate – Reliable Formation of Spheroids and Organoids

Designed for optimal spheroid culture, our high-quality CEROplate Ultra-Low Attachment bridge the gap between traditional 2D cultures and the complex in vivo environment.

Fast and Reliable Spheroid Formation

Uniform spheroids form within 2 to 24 hours (depending on cell type).

Extended 3D Culture Viability

Enables long-term cultivation of robust and functional 3D cell models.

Highly Durable Surface

Resistant to scratches and chemical exposure, ensuring lasting performances.

Minimizes Protein and Compound Binding

Reduces interactions, allowing accurate control of assay conditions.

Optimized for Spheroids and Organoids

Prevents cell attachment, supporting effective suspension cultures and organoid development.

Consistent Quality

Produced with precision, the CEROplates are sterile, endotoxin-free, and non-cytotoxic.

Microscope image of a single spheroid with its outline detected in green

Our product's ability to produce symmetrical spheroids per well enhances the consistency of your data, eliminating issues such as deposits or irregular shapes that can affect your research outcomes.

Ultra-Low Attachment Plates for Spheroid Culture

Ultra-low attachment (ULA) plates have a surface that cells cannot adhere to. Instead of spreading out as a monolayer, the cells aggregate into a spheroid. In CEROplates, uniform spheroids form within 2 to 24 hours, depending on the cell type.

CEROplates are available in four formats: 96-well and 384-well plates with U-bottom for one spheroid per well, and 6-well and 24-well plates with flat bottom. All are made of polystyrene and are sterile, endotoxin-free and non-cytotoxic. The surface is resistant to scratches and chemicals and minimises protein and compound binding.

CEROplates belong to the CERO family of consumables for the CERO 3D incubator and bioreactor.

Ultra-low attachment plates in the shop Discover the CERO 3D Bioreactor

Applications

Screen Compounds in 3D Cell Culture Systems

Mimic Extracellular Environments for Stem Cells

Establish Novel and Challenging Cell Cultures

Perform Noise-Free Biochemical Assays

Solve Your Biointerface Challenges

Available in different formats

FAQs – CEROplate

CEROplate is a specialized multi-well plate designed for 3D cell culture in the CERO 3D incubator and bioreactor. It enables the formation and maintenance of uniform spheroids and organoids, supporting applications in drug screening, cancer research, and tissue engineering.

CEROplate is compatible with a wide range of cell types, including:

Cancer cells (tumor spheroids)
Stem cells (organoids)
Primary cells
Co-cultures for studying cell-cell interactions

CEROplate is made from biocompatible, non-cytotoxic materials designed to support cell viability and growth.

No, CEROplate is designed for single-use to maintain sterility and avoid cross-contamination between experiments.

CEROplate is available as 6-well and 24-well plates with flat bottom and as 96-well and 384-well plates with U-bottom, all with an ultra-low attachment surface.

Yes, CEROplate is compatible with microscopy, fluorescence imaging, and automated high-content screening, making it ideal for real-time monitoring of 3D cultures.

If you encounter any issues or have questions, the OLS service team is available to assist you. Contact us for expert guidance on optimizing your 3D cell culture experiments.