Effortless 3D Cell Culture: Save Time, Reduce Costs, and Achieve Reliable Results


CERO 3D Incubator and Bioreactor - optimized cultivation of stem cells, spheroids, organoids and tissue biopsies



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Trusted by hundreds of labs worldwide

Successfully implemented in leading cancer and stem cell research institutions. Driving Precision and Efficiency in Cell Research 


Saving time, enhancing quality, and paving new paths


Prof. Dr. L. Sevenich and A. Wolfram


Scalable stem cell processes with minimal starting volumes.


Dr. J. Neubauer | Managing Director at Fraunhofer Project Center for Stem Cell Process Technology


CERO 3D advances liver tissue research like never before.


Prof. Dr. A. Nüssler and Prof. Dr. S. Ehnert

Your Challenges in 3D Cell Culture - Solved with CERO 3D

Researchers face numerous challenges in 3D Cell Culture:​


The cultivation and differentiation of pluripotent stem cells often result in a heterogeneous cell population. 


Organoids lose their structure and metabolic activity during long-term culture.


Time-consuming manual maintenance like media changes.


High costs for consumables and substrates.  

How CERO 3D Transforms Your Research

Level-Up Your Research with Cutting-Edge 3D Cell Culture

The CERO 3D Incubator & Bioreactor simplifies 3D cell culture like never before. With unmatched ease-of-use, adaptability for various cell types, and consistent results, it’s your key to accelerating breakthroughs in research.


Enhanced Cell Viability and Vitality

The CERO 3D’s low-shear bi-directional rotation reduces cell stress and ensures optimal nutrigen supply, supporting enhanced cell survival, maturation, and differentiation. This design minimizes damage to cell structures, allowing for long-term cultures without compromising cell quality.



Flexible & Scalable 

Suitable for a wide range of cell types—including stem cells, tumor cells, and even tissue biopsies—CERO 3D delivers high-quality 3D culture capabilities to labs of all sizes. With four disposable, individually controlled tubes, CERO 3D make it easy to scale up, replacing a full incubator while using only minimal space on the benchtop.  


Automated Environmental Control

The system offers precise control over essential culture prarmeters such as CO₂, temperature, and pH. This ensures optimal conditions for the differentiation, maturation, and growth of various cell types and 3D-structures including organoids and tissue biopsies.  



Budget-friendly & Easy handling 

Experience intuitive operation with minimal hands-on time. Special culture vessels enable 4-minute media changes, reduce media usage, and eliminate the need for embedding substrates. This ensures time- and cost-efficient cultivation of high-quality 3D structures.



Extended Culturing for Long-Term Studies

Built for durability, the CERO 3D supports cultures from days to months, making it ideal for long-term studies such as regenerative medicine, cancer research, and viral infections, as well as the complete maturation of cells.


Advanced 3D Cell Culture 

Experience realistic cell growth with 3D cell culture that promotes more realistic cell behavior and interactions compared to traditional 2D cultures, offering improved accuracy for applications in cancer research, tissue modeling, and regenerative medicine.


Increased cell vitality  and homogeneity of cell populations.



Reduced costs by optimized consumable usage.




Simplified handling and reduced manual workload.        



Reproducibility and reability you can trust.




Applications

„With CERO 3D, we increased the size of our organoids by 50% while cutting manual labor in half. Our research is now more precise and efficient.“ 

– Dr. Anna Miller, Head of Cancer Research  


Publications

See the publications reference


Pluripotent Stem Cells

Learn more about Stem Cell Expansion and Differentiation



Spheroids

Learn more about Spheroids Research Model





Tissue Biopsis

Learn more about long-term liver tissue cultivation






Track T-Cell activation

Learn how CASY works with T-Cell activation



Mor​​e Info


Pluripotent Stem Cells

Learn more about Stem Cell Expansion and Differentiation



Mor​​e Info


Spheroids

Learn more about Spheroids Research Model



Mor​​e Info


Tissue Biopsis

Learn more about long-term liver tissue cultivation



Mor​​e Info


Virus Research

Learn more about Virus Research




Cardiac Tissue Model

Learn more about CERO 3D and Cardiac Tissue Model





Organoids

Learn more about CERO 3D Tumor Tissue Model and Precision Medicine






Immunotherapy

Learn more about CERO 3D Immunotherapy








Virus Research

Learn more about Virus Research



Mor​​e Info


Cardiac Tissue Model

Learn more about CERO 3D and Cardiac Tissue Model



Mor​​e Info


Organoids

Learn more about CERO 3D Tumor Tissue Model and Precision Medicine



Mor​​e Info


Immunotherapy

Learn more about CERO 3D Immunotherapy



Mor​​e Info

FAQ

Your Questions, answered: Everything you need to know about the CERO 3D


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