Single Cell Expansion & Colony Isolation - Effortless, Precise, Scalable​


CellRaft Air® System -Automatically image, track and analyze cells or colonies of interest for downstream endpoint analysis or clonal expansion.

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cellraft air system

CellRaft Air® System

Challenges in Generation of Single Cells and Monoclonal Colonies

Poor survival rates due to high shear stress.

No control over monoclonality.

High manual workload.

High demand for consumables.

Solved by CellRaft Air

  • Gentle cell handling ensures high viability.
  • Non-invasive Monitoring.
  • Automated Cell/Colony Isolation. 
  • Reduced need of media and plastic ware.


colony isolation system

CellRaft AIR® Revolutionizing Monoclonal Colony Generation

10 - 50X More Monoclonal Colonies in Weeks, not Months

Grow single cells in a flask-live environment, ensuring the viability and vitality of single cells while they develop into clones.

Identify and Monitor

Identify cells of interest using an integrated three-channel fluorescence plus brightfield microscope with user-defined parameters.

Automated Isolation

Automatically isolate CellRafts containing cells or colonies of interest without the use of fluidics.

Image-Based Proof of Monoclonality

Create a complete image-based record of all clones to support regulatory submissions. 

Technology and Workflow

CellRaft technology revolutionizes the development of monoclonal colonies by eliminating traditional methods like trypsinization and manual cell dispensing. It uses three key components:

CellRaft Array

A specialized tissue culture dish containing thousands of microscale cell culture growth surfaces called CellRafts that provide a stable, supportive environment for single-cell growth. 

CellRaft Cytometry™ Software

Advanced software designed for precise analysis and monitoring of cell behavior. 

CellRaft AIR Platform

An integrated system that combines rapid imaging, software-guided identification, and automated isolation for high-efficiency monoclonal colony development.

This integrated system enhances the efficiency and scalability of monoclonal colony development.

CellRaft Air® Technology

CellRaft Air® System

Applications

Learn more about NovoCyte Instrument's applications

Cell line development

CRISPR gene editing

Stem cell culture

Organoid development

Single-cell genomics

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FAQs

The CellRaft AIR System is an advanced platform for single-cell isolation and analysis. It allows researchers to track, identify, and retrieve individual cells while maintaining their viability and native expression profiles. ​

Its combination of imaging, software-guided cell selection, and automated, gentle cell transfer into a multi well plate without disturbing cell integrity.

It is ideal for applications such as:

  • Cell line development
  • Stem cell culture
  • Organoid and spheroid research
  • Single cell genomics
  • CRISPR Gene editing

The system uses single-cell-resolution imaging to capture cell morphology and growth dynamics, allowing identification and tracking of cells based on user-defined phenotypic criteria.

The system isolates cells of interest without using any fluidics and without enzymatic treatments (like trypsin), preserving their natural state and minimizing stress.

It combines imaging, software-driven selection, and automated cell retrieval into one seamless workflow, reducing manual handling and improving cell recovery rates.

  No, the system works with low-input samples, making it ideal for rare cell populations or precious samples.

  Yes, isolated cells are compatible with various downstream assays, including next-generation sequencing (NGS), PCR, and proteomics.  

Yes, the system’s software allows you to set custom criteria based on cell morphology, size, and fluorescence signals.

We offer comprehensive training, technical support, and application guidance to ensure seamless operation and optimal results.

Get in touch with one of our specialist and speed the process of generating single cells with CellRaft Air®

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CellRaft Array Flyer

CellRaft Array Flyer

CRISPR Flyer

CRISPR Flyer

Organoid Flyer

Organoid Flyer

Stem Cell Flyer

Stem Cell Flyer

Species Diversity RaftNote

Species Diversity RaftNote