Publications
"Pisano, Simone; Pierini, Irene; Gu, Jianhua; Gazze, Andrea; Francis, Lewis Webb; Gonzalez, Deyarina; Conlan, Robert Steven; Corradetti, Bruna (2020)
Immune (Cell) Derived Exosome Mimetics (IDEM) as a Treatment for Ovarian Cancer.
Frontiers in Cell and Developmental Biology 8:553576"
DOI: 10.3389/fcell.2020.553576
"Linnemann, Caren; Venturelli, Sascha; Konrad, Franziska; Nussler, Andreas K; Ehnert, Sabrina (2020)
Bio-impedance measurement allows displaying the early stages of neutrophil extracellular traps.
Excli Journal; 19: 1481-1495"
"Wang, Zhiru; Kang, Wenting; Li, Ouwen; Qi, Fengyu; Wang, Junwei; You, Yinghua; He, Pengxing; Suo, Zhenhe; Zheng, Yichao; Liu, Hong-Min
Abrogation of USP7 is an alternative strategy to downregulate PD-L1 and sensitize gastric cancer cells to T cells killing.Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels
Acta Pharm Sin B. 2021 03;11(3):694-707
DOI: 10.1016/j.apsb.2020.11.005
Jin, Lan; Chen, Yunhe; Cheng, Dan; He, Zhikai; Shi, Xinyi; Du, Boyu; Xi, Xueyan; Gao, Yujing; Guo, Yang
YAP inhibits autophagy and promotes progression of colorectal cancer via upregulating Bcl-2 expression.
Cell Death Dis. 2021 01 07;12(5):457"
DOI: 10.1038/s41419-021-03722-8
Calandria, Jorgelina M; Bhattacharjee, Surjyadipta; Maness, Nicholas J; Kautzmann, Marie-Audrey I; Asatryan, Aram; Gordon, William C; Do, Khanh V; Jun, Bokkyoo; Mukherjee, Pranab K; Petasis, Nicos A; Bazan, Nicolas G
Elovanoids downregulate SARS-CoV-2 cell-entry, canonical mediators and enhance protective signaling in human alveolar cells.
Sci Rep. 2021 01 10;11(1):12324"
DOI: 10.1038/s41598-021-91794-z
"Tyumentseva, Marina A; Tyumentsev, Aleksandr I; Akimkin, Vasiliy G
Protocol for assessment of the efficiency of CRISPR/Cas RNP delivery to different types of target cells.
PLoS One. 2021;16(11):e0259812"
DOI: 10.1371/journal.pone.0259812
Bear, Adham S; Blanchard, Tatiana; Cesare, Joseph; Ford, Michael J; Richman, Lee P; Xu, Chong; Baroja, Miren L; McCuaig, Sarah; Costeas, Christina; Gabunia, Khatuna; Scholler, John; Posey, Avery D; O'hara, Mark H; Smole, Anze; Powell, Daniel J; Garcia, Benjamin A; Vonderheide, Robert H; Linette, Gerald P; Carreno, Beatriz M
Biochemical and functional characterization of mutant KRAS epitopes validates this oncoprotein for immunological targeting.Maintenance of human adipose derived stem cell (hASC) differentiation capabilities using a 3D culture
Nat Commun. 2021 01 16;12(1):4365"
DOI: 10.1038/s41467-021-24562-2
"Laura M. Mateyka, Vincent Grass, Andreas Pichlmair, Dirk H. Busch, Elvira D’Ippolito
SARS-CoV-2 CD8+ T cell killing assays using replicating viruses and transgenic antigens
STAR Protocols Volume 3, Issue 4, 16 December 2022, 101699"
DOI: 10.1016/j.xpro.2022.101699
Pratik S. Bhojnagarwala, Ryan P. O’Connell, Daniel Park, Kevin Liaw, Ali R. Ali, Devivasha Bordoloi, Joel Cassel, Nicholas J. Tursi, Ebony Gary, David B. Weiner
In vivo DNA-launched bispecific T cell engager targeting IL-13Rα2 controls tumor growth in an animal model of glioblastoma multiforme
Molecular Therapy: Oncolytics Vol. 28 March 2023"
"Albert C Yeh, Motoko Koyama, Olivia Waltner, Simone A Minnie, Julie Boiko, Tamer B Shabaneh, Shuichiro Takahashi, Ping Zhang, Kathleen Ensbey, Christine Schmidt, Samuel Legg, Tomoko Sekiguchi, Ethan Nelson, Shruti Bhise, Andrew Stevens, Tracy A Goodpaster, Saranya R. Chakka, Scott N. Furlan, Kate A. Markey, Marie Bleakley, Geoffrey R Hill
Microbiota-Specific T Cells Contribute to Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation
Blood 142 (2023) 345-347"
"Daniel H. Park, Kevin Liaw, Pratik Bhojnagarwala, Xizhou Zhu, Jihae Choi, Ali R. Ali, Devivasha Bordoloi, Ebony N. Gary, Ryan P. O’Connell, Abhijeet Kulkarni, Diana Guimet, Trevor Smith, Alfredo Perales-Puchalt, Ami Patel, and David B. Weiner
Multivalent in vivo delivery of DNA-encoded bispecific T cell engagers effectively controls heterogeneous GBM tumors and mitigates immune escape
Molecular Therapy Oncolytics (2023)"
DOI: 10.1016/j.omto.2023.02.004
Carla A. Jaeger-Ruckstuhl, Yun Lo, Elena Fulton, Lucas B. Sullivan, Scott N. Furlan, Stanley R. Riddell
Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
Immunity (2024) 57, 287–302."
DOI: 10.1016/j.immuni.2024.01.011
"Tamer Basel Shabaneh, Andrew R Stevens, Sylvia M Stull, Kristen R Shimp, Brandon W Seaton, Ekram A Gad, Carla A Jaeger-Ruckstuhl, Sylvain Simon, Amanda L Koehne, Jason P Price, James M Olson, Benjamin G Hoffstrom, David Jellyman, Stanley R Riddell
Systemically administered low-affinity HER2 CAR T cells mediate antitumor efficacy without toxicity
Journal for ImmunoTherapy of Cancer 2024;12:e008566
Long Yang , Pinsheng Han , Tao Cui, Yu Miao , Tianyu Zhao, Zilin Cui, Yijia Chen, Hao Chi, Jieying Zhang, and Yamin Zhang
M2 macrophage inhibits the antitumor effects of Lenvatinib on intrahepatic cholangiocarcinoma
Front. Immunol. 14:1251648
DOI: 10.3389/fimmu.2023.1251648
"Valeria Khaimov, Julia Strübing, Thomas Stahnke, Niels Grabow, Klaus-Peter Schmitz,and Stefan Siewert
A time-resolved fibrosis model – in vitro assessment of antifibrotic implant coatings
Current Directions in Biomedical Engineering 2022;8(2): 297-300"
"Caren Linnemann , Sascha Venturelli, Franziska Konrad, Andreas K. Nussler, Sabrina Ehnert
Bio-impedance measurement allows displaying the early stages of neutrophil extracellular traps
EXCLI Journal 2020;19:1481-1495"
"Simone Pisano, Irene Pierini, Jianhua Gu, Andrea Gazze, Lewis Webb Francis, Deyarina Gonzalez, Robert Steven Conlan and Bruna Corradetti
Immune (Cell) Derived Exosome Mimetics (IDEM) as a Treatment for Ovarian Cancer
Frontiers in Cell and Developmental Biology (2020)"
DOI: 10.3389/fcell.2020.553576
"Chris P Miller, Megan Fung, Carla A Jaeger-Ruckstuhl, Yuexin Xu, Edus H Warren, Shreeram Akilesh, Scott S Tykodi
Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system
Neoplasia. 2023 Dec;46:100948."
DOI: 10.1016/j.neo.2023.100948
"Bakir Valentić, Andre Kelly, Alexander A. Shestov, Zhiyang Gan, Feng Shen, Adam Chatoff, Alison Jaccard, Claudia V. Crispim, John Scholler, Simon Heeke, Nathaniel W. Snyder, Saba Ghassemi, Nicholas Jones, Saar Gill, Roddy S. O’Connor
The Glucose Transporter 5 Enhances CAR-T Cell Metabolic Function and Anti-tumour Durability."
DOI: 10.21203/rs.3.rs-4342820/v1
"Sarah E. Scheuermann, Kelly Goff, Lori A. Rowe, Brandon J. Beddingfield, and Nicholas J. Maness
Real-Time Analysis of SARS-CoV-2-Induced Cytolysis Reveals Distinct Variant-Specific Replication Profiles
Viruses 2023, 15, 1937."
"Mauricius Marques dos Santos, Caixia Li, Shenglan Jia, Mikael Thomas, Hervé Gallard, Jean-Philippe Croué, Pascal Carato, Shane Allen Snyder
Formation of halogenated forms of bisphenol A (BPA) in water: Resolving isomers with ion mobility – mass spectrometry and the role of halogenation position in cellular toxicity
J Hazard Mater. 2024 Mar 5:465:133229"
DOI: 10.1016/j.jhazmat.2023.133229
"Xiaohu Liu, Zahid Delwar, Jun Ding, Guoyu Liu, Olga Tatsiy, Dmitry Chouljenko, Gregory Hussack, Henk Van Faassen, William Wei-Guo Jia, Yanal M. Murad, I-Fang Lee
HSV-1 Oncolytic Virus Targeting CEACAM6-Expressing Tumors Using a Bispecific T-Cell Engager
bioRxiv 2023.01.02.522257"
DOI: 10.1101/2023.01.02.522257
"Erica T Goddard, Miles H Linde, Shivani Srivastava, Grant Klug, Tamer B Shabaneh, Santino Iannone, Candice A Grzelak, Sydney Marsh, Alessandra I Riggio, Ryann E Shor, Ian L Linde, Marissa Guerrero, Joshua R Veatch, Annelise G Snyder, Alana L Welm, Stanley R Riddell, Cyrus M Ghajar
Immune evasion of dormant disseminated tumor cells is due to their scarcity and can be overcome by T cell immunotherapies
Cancer Cell, Volume 42, Issue 1, 119-134.e12, 2024. "
DOI: 10.1016/j.ccell.2023.12.011
"Zhen Wang, Shu-ying Yi, Yuan-ying Zhang, Yu-di Wang, Han-lin Chen, Yi-jie Guo, Xin-ming Wei, Du-xiao Yang
The role of vitamin D through SphK1/S1P in the regulation of MS progression
J Steroid Biochem Mol Biol. 2024 Feb:236:106425."
DOI: 10.1016/j.jsbmb.2023.106425
"Mauricius Marques dos Santos, Camille Cheriaux, Shenglan Jia, Mikael Thomas, Hervé Gallard, Jean-Philippe Croué, Pascal Carato, Shane Allen Snyder
Genotoxic effects of chlorinated disinfection by-products of 1,3-diphenylguanidine (DPG): Cell-based in-vitro testing and formation potential during water disinfection
J Hazard Mater. 2022 Aug 15:436:129114."
DOI: 10.1016/j.jhazmat.2022.129114
"Ryan P O’Connell, Kevin Liaw, Nils Wellhausen, Christopher A Chuckran, Pratik S Bhojnagarwala, Devivasha Bordoloi, Daniel Park, Nicholas Shupin, Daniel Kulp, Carl H June, and David Weiner
Format-tuning of in vivo-launched bispecific T cell engager enhances efficacy against renal cell carcinoma
Journal for Immunotherapy of Cancer (2024)"
"S. Huerta-Yepez, Po-Chun Chen, Kawaljit Kaur, Yash Jain, Tanya Singh, Favour Esedebe, Yi Jou Liao, Gabriella DiBernardo, Neda A Moatamed.
Supercharged NK cells, unlike primary activated NK cells, display antitumor activity in multiple mouse tumor models and mediate long-term protection
BMJ Oncology (2025)"
DOI: 10.1136/bmjonc-2023-000618
"Baolong Pan, Simon JMountford, Maki Kiso, Danielle E Anderson, Georgina Papadakis, Kate E Jarman, Danielle R Tilmanis, Belinda Maher, Thomas Tran, Jake Shortt, Seiya Yamayoshi, Yoshihiro Kawaoka, Philip E Thompson, Sam A Greenall, Nadia Warner
Targeted protein degraders of SARS-CoV-2 Mpro are more active than enzymatic inhibition alone with activity against nirmatrelvir resistant virus
Communications Medicine (2025)"
DOI: 10.1038/s43856-025-00863-1
"Paola Bonaventura, Audrey Page, Olivier Tabone, Yann Estornes, Virginie Mutez, Marie Delles, Sarah Moran, Clarisse Dubois, Thibault Richard, Marjorie Lacourrege, Marie Michelas, Dina M Tawfik, Ema Etchegaray, Adrian Valente, Rasha E Boulos, Gabriel Jimenez Dominguez, Isabelle Treilleux, Nicolas Chopin, Olivia Le Saux, Nicolas Chuvin, Nicolas Gadot, Maha Ayyoub, Qing Wang, Jenny Valledeau-Guilemond, Stephane Depil.
HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Journal for Immunotherapy of Cancer (2025)"
"Shushu Zhao, Yeqing Chen, Pratik S Bhojnagarwala, Cory Livingston, Joshua Jose, Yangcheng Gao, Daniel H Park, Meenhard Herlyn, David B Weiner
Targeting IL13Rα2 in melanoma with a bispecific T-cell engager: expression profiling and preclinical evaluation
Journal for Immunotherapy of Cancer (2025)"
"Lu Xia, Hexin Lin, Huifen Cao, Jiabian Lian.
Tenascin C as a novel zinc finger protein 750 target regulating the immunogenicity via DNA damage in lung squamous cell carcinoma
BMC Cancer (2024)"
DOI: 10.1186/s12885-024-12285-8
"Yu Kato, Nathaniel Rice, Michael Pokrass, Jinkil Jeong, Ruben Rodriguez, Jessica J.Field, and Heba Nowyhed
Nonclinical characterization of ICVB-1042 as a selective replicating oncolytic adenovirus for cyclin D–expressing tumors
Communications Biology (2024)"
DOI: 10.1038/s42003-024-06839-6
"Daniel H Park, Pratik S Bhojnagarwala, Kevin Liaw, Devivasha Bordoloi, Nicholas J Tursi, Shushu Zhao, Zev A Binder, Donald O'Rourke, David B Weiner
Novel tri-specific T-cell engager targeting IL-13Rα2 and EGFRvIII provides long-term survival in heterogeneous GBM challenge and promotes antitumor cytotoxicity with patient immune cells
Journal for Immunotherapy of Cancer (2025)"
"Yi Zhang, Miso Park, Lucy Y Ghoda, Dandan Zhao, Melissa Valerio, Ebtesam Nafie, Asaul Gonzalez, Kevin Ly, Bea Parcutela, Yeran Choi, Xubo Gong, Fang Chen, Katio Harada, Zhenhua Chen, Le Xuan Truong Nguyen, Flavia Pichiorri, Jianjun Chen, Joo Song, Stephen J Forman, Idoroenyi Amanam, Bin Zhang, Jie Jin, John C Williams, Guido Marcucci
IL1RAP-specific T cell engager depletes acute myeloid leukemia stem cells
Journal of Hematology & Oncology (2024)"
DOI: 10.1186/s13045-024-01586-x
"Franziska Fuchsl, Johannes Untch, Vladyslav Kavaka, Gabriela Zuleger, Sarah Braun, Antonia Schwanzer, Sebastian Jarosch, Carolin Vogelsang, Niklas de Andrade Kratzig, Dario Gosmann, Rupert Ollinger, Piero Giansanti, Michael Hiltensperger, Roland Rad, Dirk H Busch, Eduardo Beltran, Eva Braunlein, Angela M Krackhardt.
High-resolution profile of neoantigen-specific TCR activation links moderate stimulation to increased resilience of engineered TCR-T cells
Nature Communications (2024)"