Cytotoxicity Assay for Anti-Cancer Drugs - Fast & Reliable Analysis
Why Cytotoxicity Assays Matter in Cancer Research
Chemotherapy drug combinations, such as epirubicin, cisplatin, and fluorouracil (ECF), are widely used in gastric cancer treatment. However, new drug combinations may provide greater efficacy and fewer side effects.
Key Features of CASY Cytotoxicity Assays
Precise viability analysis without the need for staining
Exclusion of dead cells and debris for accurate results
Statistically relevant data from triplicate measurements
Monitoring of cell growth inhibition in real-time
Evaluating the cytotoxicity of anti-cancer drug combinations
In a recent study, Dr. Weinreich used the CASY Cell Counter to assess chemosensitivity and cell viability in gastric adenocarcinoma and non-malignant cell lines.
The CASY Cytotoxicity Assay was used to measure growth inhibition over 5, 10, and 14 days.
Results demonstrated that the D-D chemotherapy regimen was more effective against malignant gastric cancer cells than non-malignant cells, making it a promising alternative to standard treatments.
References: Weinreich J, Archid R, Bajaeifer K, Hack A, Königsrainer A, Schott TC. Growth and Chemosensitivity of Gastric Adenocarcinoma and Non-Malignant Cell Lines in Response to Novel Anti-Cancer Drug Combinations. Chemotherapy. 2014; 60(5-6):346-352. DOI: 10.1159/000438943. Epub 2015 Aug 29.
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