Virus Research

CERO 3D Incubator & Bioreactorrevolutionizes 3D cell culture by enabling the growth and maturation of spheroids without necrosis or apoptosis, outperforming traditional technologies.

It reliably maintains a wide range of 3D models, including Huh7 hepatic spheroids, delivering superior results for diverse applications.

The innovative disposable CEROtubes with integrated HEPA filters create a secure environment for virus experiments. This unique feature supports the safe and effective study of viral infections within 3D cultures, opening new possibilities in virology and advanced cell biology.

Virus Infection Studies

Hepatocyte spheroids were matured for 20 days before being exposed to Hepatitis C Virus (HCV) at an infectious dose of 1000. Viral spread was monitored at 24, 48, and 72 hours post-infection, with brown staining indicating NS5A expression to track infection progression over time.

HCV replication in Huh7-derived hepatocyte spheroids 24 hours after infection, infected areas in brown

24h

HCV replication in Huh7-derived hepatocyte spheroids 48 hours after infection, infected areas in brown

48h

HCV replication in Huh7-derived hepatocyte spheroids 72 hours after infection, infected areas in brown

72h

HCV replication in Huh7 derived hepatocyte spheroids was tracked at 24h, 48h, and 72h post viral infection (brown areas)

Quantification of the infection experiment over time

Quantification of the overall infection experiment over time.

Revolutionize Virus Research with 3D Cell Culture.

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