Virus Research
Learn more about Virus Research
Virus Research
CERO 3D Incubator & Bioreactor enables growth and maturation of spheroids without necrosis and apoptosis while other technologies fail. Therefore, CERO 3D allows to maintain state-of-the-art 3D cultures, for example of Huh7 hepatic cell line. Disposable CEROtubes with HEPA filters provide a secure environment for virus experiments, enabling the study of viral infections within 3D cultures safely and effectively.
Enables Virus Infection Studies
Quantification of the overall infection experiment over time. Size of scale bars is indicated.
24h
48h
72hHepatocyte spheroids were matured for 20 days before being exposed to Hepatitis C Virus (HCV) at an infectious dose of 1000. Viral spread was monitored at 24, 48, and 72 hours post-infection, with brown staining indicating NSSA expression to track infection progression over time.
HCV replication in Huh7 derived hepatocyte spheroids was tracked at 24h, 48, and 72h post viral infection (brown areas).
24H
48H
72H
Matured shperoids where infected with 1000 infectious of Hepatitis C Virus (HVC)
Degree of infection over time was tracked by:
Staining (brown areas)
NSSA expression
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