xCELLigence RTCA DP - Cell Invasion & Migration 

xCELLigence RTCA DP (dual purpose) system provides label-free, real-time monitoring of cell health, behavior, and additionally invasion/migration. Designed for flexibility and throughput, the system supports up to three 16-well plates simultaneously, offering a total of 48 wells for parallel experiments.


Highest Flexibility: Operate up to three 16-well plates independently or simultaneously, enabling 48 wells to run in parallel for optimal productivity.

Migration and Invasion Studies: CIM-Plate 16 features electronically integrated Boyden chambers for real-time monitoring of cell invasion and migration without the need for labels or dyes.

Non-Invasive Impedance Assays: E-Plate 16 enables label-free, real-time impedance-based measurements of cell health, viability, and treatment responses with exceptional sensitivity and reproducibility.

Short- and Long-Term Analysis: Capture dynamic cell behavior with data acquisition intervals ranging from seconds to days, providing comprehensive kinetic profiles.

Easy Workflow: Simply add cells to the plates, start kinetic measurements under physiological conditions, and reduce hands-on time with an intuitive process.

Powerful RTCA Software Pro: Analyze real-time data to generate diverse plot types and automatically calculate critical parameters like % cytolysis, IC50, or KT50.

Regulatory Compliance: RTCA Software Pro supports FDA 21 CFR Part 11 compliance, ensuring secure electronic data integrity for research and regulatory standards.

Typical Applications

Technical Specifications


Plate formats: 

E-Plate 16, CIM-Plate 16.


Well throughput: 

Up to 48 wells (3 × 16-well plates)​


Data acquisition: 

From seconds to days


Control software: 

RTCA Software Pro with compliance features


Compliance: 

FDA 21 CFR Part 11 (audit trails, secure data)