xCELLigence RTCA eSight: Combining Impedance-Based Measurement with Live Cell Imaging 

The eSight is the first system that integrates the high sensitivity of label-free impedance-based analysis with live cell imaging. Simultaneously evaluate both modes for unparalleled insights into cellular behavior and underlying mechanisms.


  • Integrated Real-Time Cell Analysis & Imaging: Combine label-free impedance-based cell monitoring with live-cell imaging in red, green, and blue fluorescence, utilizing 5x, 10x, and 20x objectives for deeper insights and confidence in your conclusions.
  • Whole-Well Imaging: Expand visualization to capture the entire well, ideal for quality control and precise quantification of cell growth and behavior.
  • Multiplexed, Information-Rich Assays: Simultaneously combine cellular impedance and live-cell imaging in the same well, within your incubator, for more informative and efficient assays.
  • Flexible Workflow: Adapt seamlessly to diverse experimental protocols while monitoring cell health, morphology, behavior, and function in real-time in both 2D and 3D cell cultures.
  • Flexible Imaging Capabilities: Utilize brightfield and three fluorescent channels across multiple microplate formats (6- to 384-well plates) and vessel types (35 or 60 mm dishes), with user-defined schedules for tailored analysis.
  • Comprehensive Data: Continuously measure cell number, proliferation, size, morphology changes, and cell-substrate attachment quality for a better understanding of cellular activity.

Typical Applications

  • Immune Cell Killing Assays
  • Viral Cytopathic Effect Assays
  • Cytotoxicity Assays
  • Apoptosis and Proliferation Assays
  • Phagocytosis